Maureen Hoane 1
Methods
This case report details the clinical presentation, radiographic findings, cytology, fluid analysis, histopathology, and treatment approach for a juvenile Great Dane with MPO. The diagnostic process included fine-needle aspiration, skull radiographs, intraoral biopsy, and histopathological analysis. Follow-up was conducted over a 16-week period to monitor resolution.
Results
Radiographic examination revealed a “double cortex” on the left caudal mandible, characteristic of MPO. Cytology of aspirated fluid showed a moderate mixed cell infiltrate without signs of infection or neoplasia. Histopathology of bone samples identified proliferating woven bone with fibrous connective tissue and no inflammation or malignancy. The lesion gradually regressed over time with no intervention beyond monitoring, and the dog exhibited normal dental eruption and occlusion by the final follow-up.
Limitations
The case report discusses a single animal, limiting generalizability. Histological findings were nonspecific and did not definitively exclude other conditions. The exact etiology of MPO remains uncertain, and trauma, although suspected, was not conclusively linked.
Conclusions
This case supports the diagnosis of MPO as a benign, self-resolving mandibular swelling in young, large breed dogs. Radiographic identification of the double cortex and exclusion of other conditions are key to diagnosis. Conservative management through observation is typically effective. The report emphasizes the potential for further research using advanced imaging modalities like CBCT to better understand MPO's pathogenesis and risk factors.
Intraoral radiographs of the left caudal mandible showing a “double cortex” (arrow): (a) parallel view and (b) occlusal view.
How did we do?
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