Computed tomographic findings may be useful for differentiating small intestinal adenocarcinomas, lymphomas, and spindle cell sarcomas in dogs

Seonah Lee, Jeongyeon Hwang, Hyunwook Kim, Yeonjung Hong, Gahyun Lee, Doori Chung, Jaehwan Kim, Kidong Eom

Background: The paper aims to improve understanding of CT characteristics for histologically confirmed primary intestinal tumors in dogs to guide prognosis and treatment plans.

Study: This is a retrospective, multi-center, analytical study.

Methods: The study evaluated CT characteristics for differentiation of adenocarcinoma, lymphoma, and spindle cell sarcoma (SCS) in 37 dogs who underwent contrast CT and histopathological examinations. Quantitative and qualitative CT parameters were evaluated for each included small intestine tumor CT case.

Results: Adenocarcinomas tended to show endophytic growth, intestinal obstruction, and a heterogeneous enhancement pattern. Lymphomas tended to show exophytic growth, contrast enhancement of the intestinal tumor mucosal layer, a homogeneous enhancement pattern, and the presence of lymphadenopathies in the abdominal cavity. SCSs tended to show lobulated growth, a large cystic portion within the tumor, a heterogeneous enhancement pattern, a large size with fat stranding sign, and lower HU values in postcontrast images. Cut-off values were derived to discriminate SCS from the two other tumor types.

Limitations: The study has several limitations, including a small sample size, not considering the effects of dog breed, age, and sex, and not classifying spindle cell sarcomas into specific subtypes. Interpretation of CT parameters might vary and discrepancies in the CT protocol may affect evaluations. Despite these limitations, the CT interpretation results were similar to those reported in a human study.

Conclusions: Contrast CT characteristics may be useful in differentiating small intestinal adenocarcinomas, lymphomas, and SCSs in dogs.

Disclaimer: The summary generated in this email was created by an AI large language model. Therefore errors may occur. Reading the article is the best way to understand the scholarly work. The figure presented here remains the property of the publisher or author and subject to the applicable copyright agreement. It is reproduced here as an educational work. If you have any questions or concerns about the work presented here, reply to this email.

The View Box runs on AI and caffeine. If you want to buy me a coffee, feel free to upgrade. A coffee in my cafeteria is $2.07. If you want to buy me one coffee pick a yearly subscription. If you want to buy one a month, pick the monthly subscription.

There are no benefits to premium subscription.