Is it possible to MRI a fish brain at 3T?

VRU 64(1): 75-85

Aim: The study aimed to determine if advanced neuroimaging can be safely achieved in live fish using clinically available equipment, optimize imaging parameters, and develop a comparative MRI atlas of a few fish species of economic or research value.

Method: Two each of channel catfish, koi, and grass carp of at least 30 cm in length were individually anesthetized for 3T MRI of the brain. Diagnostic quality images were obtained for all subjects.

Results: Findings supported the use of 3T MRI as an adjunct diagnostic test for fish with suspected neurologic disease and provided a limited anatomic atlas of the teleost brain for use as a reference.

3T MRI, sagittal plane T2w images, of the brain of a catfish (A), koi (B) and grass carp (C), and corresponding histology on the right. Major anatomic divisions of the brain are labeled. TO: telencephalon OT: optic tectum C: cerebellum M: medulla P: pituitary gland H: hypothalamus SV: saccus vasculosus Th: thalamus CN II: optic nerve. Notice the granular material dorsal to the brain and pericerebral fluid, most abundant in the koi. Technical parameters are found in Supplement 2

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