Does renal cortical thickness change in dogs with CKD?

VRU 64(1): 140-148

Ultrasonographic quantitative evaluation of acute and chronic renal disease using the renal cortical thickness to aorta ratio in dogs

Study Purpose: To determine if there are differences between actual and predicted RCT considering physical factors in dogs with renal disease and to demonstrate whether the RCT:Ao ratio index would be useful for evaluating renal pathology.

Methodology: A total of 54 dogs with acute or chronic renal disease and 30 normal healthy dogs were included in this multi-center, retrospective, analytical study. The RCT was measured at the center of the renal pyramid and the diameter of the Ao was measured just caudal to the branch of the left renal artery in systole.

Results: The RCT:Ao ratio was significantly different between normal dogs and dogs with CKD or AKI. The RCT:Ao ratio can be used as a non-invasive quantitative method for characterizing kidney pathology in dogs with acute or chronic renal disease.

Sagittal plane ultrasound, in vivo B-mode images of a canine kidney (A) and adjacent aorta (B) acquired using a 13 MHz linear array transducer. RCT was measured at the center of each renal pyramid as the shortest distance (double-headed arrow) perpendicular to the trailing edge of renal capsule from the leading edge of the base of the renal medullary pyramid on the mid-sagittal plane image of the kidney at 3 points and the values were averaged (A). The diameter of the Ao (double-headed arrow) was measured in systole for maximal luminal diameter just caudal to the branch of the left renal artery (asterisk) in the sagittal plane (B) Ao, abdominal aorta; RCT, renal cortical thickness

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