What is the best way to image a mast cell tumor?

VRU 64(1): 53-60

CT features of subcutaneous, intermuscular, and intramuscular mast cell tumors in dogs

The article aims to describe the imaging features of subcutaneous, intermuscular, and intramuscular mast cell tumors (MCTs) in dogs and to assess the limitation of CT to identify the full local extent of the MCT. The authors used histology and/or CT scan to diagnose MCTs in 16 dogs and reviewed the CT images by two radiologists. They recorded the location, contrast enhancement pattern, and delineation of the MCTs. They found that CT had low sensitivity and specificity for determining location (SC/InterM versus IntraM) and low inter-rater agreement for delineation. They also found that CT findings were insufficient for curative surgical planning in 13 of 16 cases due to inadequate definition of tumor depth, compartment boundary, or MCT margins. The authors concluded that CT has limitations for presurgical planning of MCTs in dogs and suggested further research to improve the diagnostic accuracy and utility of CT.

Post contrast computed tomographic (A, B, C, G, H, I) and T1w MRI (D, E, F,J, K, L) images of a right caudomedial thigh (A–F) and left caudolateral thigh (G–L) mast cell tumor. Images are paired at the same level in transverse (A and D, G and J), dorsal (B and E, H and K) and sagittal (C and F, I and L) planes. The lesion (arrow) was better defined in the T1W post contrast MR images when compared to the post contrast CT images. Image acquisition technical parameters for CT images were ‘standard’ reconstruction kernel, WW: 400, WL: 40, Slice thickness: 0.625 mm; and for MRI images were T1 post contrast 1 mm isotropic slices.

How did we do?

Login or Subscribe to participate in polls.

Disclaimer: The summary generated in this email was created by an AI large language model. Therefore errors may occur. Reading the article is the best way to understand the scholarly work. The figure presented here remains the property of the publisher or author and subject to the applicable copyright agreement. It is reproduced here as an educational work. If you have any questions or concerns about the work presented here, reply to this email.